Close species comparative genomics

Close Species Comparative Genomics

Jong Bhak

Abstract:

It is a subfield of comparative genomics where close but distinctive enough species genomes are compared.

The closeness is for genomic similarity enough to pin-point the variations while distant/distinctive part is phenotype divergence

that is sufficiently describable at genetic level.

The first large scale CSCG was done by tiger and other cat genome analyses where there became a number of close species were

sequenced and compared to explain distinct phenotypes that could be linked to clear genotypes.

Conclusion

Close species comparative genomics is useful to accurately pin-point geno- and phenotype associations in different species that

are close enough to each other.

Reference

http://www.nature.com/ncomms/2013/130917/ncomms3433/full/ncomms3433.html

http://www.nature.com/ng/journal/v46/n1/full/ng.2835.html