Phenome

From Omics.org

Jump to: navigation, search

A phenome is the set of all phenotypes expressed by a cell, tissue, organ, organism, or species. A phenome includes phenotypic traits due to either genetic or environmental influences. Just as the genome and proteome signify all of an organism's genes and proteins, the phenome represents the sum total of its phenotypic traits. Some examples of human phenotypes are skin color, eye color, height, or specific personality characteristics. Phenotypic differences between individuals can be due to environmental influences, genetic variation such as single nucleotide polymorphisms (SNPs), or a combination of the two. Phenomics is the study of the nature of phenotypes and how they are determined, particularly when studied in relation to the set of all genes (genomics) or all proteins (proteomics). 


External links

RIKEN Arabidopsis Phenome Information Database 
RAPID is a searchable site of phenotypic data in transposon-insertional mutants of Arabidopsis. RAPID represents about 4,000 transposon insertion lines which have the Ds transposon in gene coding region, and observed visible phenotypes systematically depend on growth stage. Phenotypic descriptions were classified into eight primary and fifty secondary categories, then all recorded images can be searched by the line number or the phenotype categories.
 


 Mouse Phenome Project

The MPD website will enable investigators to identify appropriate strains for:

  • physiological testing
  • drug discovery
  • toxicology studies
  • mutagenesis
  • disease onset and susceptibility
  • new models of human disease
  • QTL analyses and identification of new genes
  • unraveling the influence of environment on genotype 

    Canine Phenome Project 

    The Canine Phenome Project is an effort to describe the dog as a species in all of its variability and to understand the factors, both genetic and non-genetic, that contribute to this variability. It is an open-ended attempt to describe and understand the basis for all of the characteristics (or phenotypes) of dogs in great detail. The emphasis will be on describing those characteristics that distinguish one breed from another and those characteristics that distinguish one individual from another within a breed. In this context we consider the canine phenome to consist of all aspects of the dog including size, anatomy and appearance, composition and metabolism, behavior and temperament, and health and disease susceptibility. 


    C.elegans RNAi Phenome Database

    The genome of C. elegans was completely sequenced and approximately 20,000 genes are predicted. To identify genes that play crucial roles in the developmental program of this organism, They have been performing a systematic analysis of gene functions in C. elegans by a high-throughput RNA interference (RNAi)
  •  

    Links

    Phenome.info

     

     

    Personal tools
    Google AdSense